Deliver visible results
to your customers

Our complete range of highly concentrated professional microneedling serums.


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Sérums microneedling

Our comprehensive range

± 20min

per session


skin indications treated


specialized serums

Jusqu'à 750

per package

Innovation and performance

Discover our innovative range of highly concentrated serums for professional microneedling, specially designed for optimum synergy with our C-PEN and Electroporation.


High concentration

Serums with high doses of hyaluronic acid and other powerful active ingredients.


Wide range

Each C-EM serum is designed to target specific skin problems.


Safety and purity

Manufactured to strict ISO 91722:2015 standards in a pharmaceutical laboratory in Italy.


Optimum serum efficacy

2-stage operation

Discover the remarkable effects of our professional microneedling serums, designed to deliver results that are both immaculate and long-lasting:

  1. immediate effect: Thanks to the high concentration of 3 molecular weight (L/M/H) hyaluronic acid, your customer can immediately see the effects of the treatment on their skin, visibly smoother and plumper.

  2. Long-term effect: Gradually, the effect of hyaluronic acid fades to make way for the effects of the other active ingredients contained in our professional microneedling sérums. These active ingredients tackle your customers' specific problems and remain visible for several months.

2-stage operation

Complementary techniques

Optimum synergy

Our serums are specially designed to work in synergy with methylation techniques such as microneedling and lectroporation:


  • Microneedling: Uses microneedles to create micro-perforations thus entraining the healing process, which allows natural activation of collagen and lastin fiber synthesis.Thanks to the micro-channels created by the microneedling mechanism, the skin absorbs much more easily the active ingredients contained in the sérum used;

  • Électroporation: Uses électric pulses to temporarily open the skin's pores, thereby increasing the absorption of active ingredients from sérums. These micro-aggressions stimulate fibroblasts to produce more collagen and lastine

These methods optimize product pénétration and stimulate skin regeneration, maximizing treatment efficacy.

Optimum synergy

A complete range

Treat up to 16 skin indications!

Because every skin is unique and every one of your customers deserves the best, we've developed a comprehensive range of highly concentrated serums.

With our 9 C-EM you'll be able to treat up to 16 skin indications and attract a new customer base in search of excellence and concrete results:

Our serums are manufactured in our pharmaceutical laboratory in Italy according to ISO 9001:2015 and ISO 22716, extremely strict production standards for cosmetic products, giving them exceptional purity and quality for safe skin care. What's more, all our fragrances are guaranteed to be fragrance-free, paraben-free, PEG-free, alcohol-free and colorant-free.

Dehydration and drynessWrinkles and fine linesScars and stretch marksHyperpigmentationSmudgesSensitivityRednessSkin saggingPhotoageingLoss of radiancePuffiness and dark circlesHair loss


Our state-of-the-art formulation

Remarkable efficiency

Proven dual effectiveness: immediate and long-term

Unique formulation

Highly concentrated in pharmaceutical-grade active ingredients

Our state-of-the-art formulation

Customer satisfaction

Immediately visible results for customer satisfaction and loyalty.

Maximum comfort

A feeling of freshness and comfort during and after treatment thanks to soothing active ingredients

Customized care

A complete range of 9 professional serums for microneedling and mesotherapy to treat all skin types and problems.

Skin conditions.

Hydra Repair

Dry, dehydrated skin

Formulated to maximize skin hydration over the long term. It fortifies the skin's moisture barrier, optimizing water retention at the heart of the tissues. From the very first application, skin looks radiant, visibly smoothed and plumped thanks to its high concentration of hyaluronic acid and Glucosamine, for a healthy, revitalized appearance.
  • Indication
    • Dehydration
    • Dry skin
    • Fine lines and wrinkles
    • Scars
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin B5
    • Glucosamine
    • Niacinamides
    • Lactic Acid
    • Allantonine
  • All the ingredients

    Aqua, Niacinamide, Sodium Hyaluronate, Glycerin, Glucosamine Sulphate, Calcium Pantothenate, Lactic Acid, Phenoxyethanol, Allantoin, Polysorbate 20, Pseudoalteromonas Ferment Extract, Linseed Acid, Saccharo- myces Cerevisiae Extract, Saccharide Isome- rate, Ammonium Acryloyldimethyltaurate/ Vp Copolymer, Imidazolidinyl Urea, Capry- lyl Glycol, Xanthan Gum, Hyaluronic Acid, Butylene Glycol, Ethylhexylglycerin, 1,2-Hexa nediol, Proline, Serine, Alanine, Silanetriol, Sorbic Acid, Sodium Hydroxide, Acetyl Heptapeptide-4, Citric Acid, Sodium Phosphate, Sodium Citrate.

Sensitive care

Sensitive and reactive skin

Formulated with calming and protective active ingredients, this serum is specially designed to reduce redness, irritation and itching. Thanks to the highly soothing properties of bilberry extract and brown seaweed, it is perfectly suited to the most sensitive, delicate and demanding skin, offering immediate relief and reinforced protection against external aggressions.
  • Indication
    • Sensitive skin
    • Redness and couperose
    • Inflammations
    • Itching
    • Rosacea
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin C
    • Bilberry extract
    • Glucosamine
    • Peptides
    • Red and brown algae (rich in minerals and amino acids)
  • All the ingredients

    Aqua, Sodium Hyaluronate, Ascorbic Acid, Vac- cinium Myrtillus Extract, Linseed Acid, Butylene Glycol, Sorbitol, Maltodextrin, Allantoin, Aspara- gopsis Armata Extract, Malus Domestica Fruit Cell Culture Extract, Ascophyllum Nodosum Extract, Pseudo-alteromonas Ferment Extract, Ceramide 3, Phenoxyethanol, Polysorbate 20, Glycerin, Am- monium Acryloyldimethyltaurate Vp Copolymer, Sodium Lauroyl Lactylate, Imidazolidinyl Urea, Xanthan Gum, Caprylyl Glycol, Palmitoyl Tripep- tide-8, Dextran, Ethylhexylglycerin, Cholesterol, Ceramide 6 Ii, Phytosphingosine, Hyaluronic Acid, Silanetriol, Melatonin, Citric Acid, Lecithin, Serine, Alanine, Proline, Glycine Soja Oil, Acetyl Tetrapeptide-40, Acetyl Heptapeptide-4, Hydro- genated Lecithin, Ceramide 1, Sh-Polypeptide-9, Carbomer, Sodium Phosphate, Sodium Oleate, Disodium Edta, Sodium Hydroxide, Potassium Sorbate, Sorbic Acid.


Hyper pigment

Spots and uneven skin tone

Designed to effectively address all types of pigmentation spots, including those resulting from photoaging and melasma, as well as complexion irregularities, this advanced serum offers immediate brightening visible from the very first application. It works to restore perfect evenness and revive skin's natural radiance by actively targeting discoloration and hyperpigmentation. Thanks to its innovative active ingredients, it limits melanin production, ensuring a lasting improvement in skin evenness and luminosity.
  • Indication
    • Uneven skin tone
    • Hyperpigmentation
    • Melasma / Chloasma
    • Various spots
    • Photoaging
  • Active ingredients
    • Phytic Acid
    • Kojic Acid
    • Azelaic Acid
    • α-Arbutin
    • Rapeseed extract
    • Allantoin
    • Glucosamine
    • Peptides
  • All the ingredients

    Aqua, -Arbutin, Niacinamide, Azelaic Acid, Kojic Acid, Sodium Hyaluronate, Phytic Acid, Glycerin, Hydroxyethylcellulose, Glucosamine Sulphate, Tranexamic Acid, Allantoin, Hydro- lized Brassica Napus Seedcake Extract, Hya- luronic Acid, Ammonium Acryloyldimethyl- taurate/Vp Copolymer, Phenoxyethanol, Imi- dazolidinyl Urea, Silanetriol, Sh-Polypeptide- 11, Sh-Polypeptide-1, Citric Acid, Butylene Glycol, Sodium Oleate, Glycine Soja Oil, Hydrogenated Lecithin, Disodium Edta, Sorbic Acid.

Pure Clean

Oily skin and blemishes

PureClean's powerful active ingredients are specially selected to soothe skin reactions, delicately moisturize and regulate sebum secretion with remarkable precision, effectively preventing the appearance of new breakouts while significantly reducing existing imperfections. This innovative treatment is the key to visibly smoother, more even skin.
  • Indication
    • Acne-prone skin
    • acne-prone
    • Excess sebum
    • Dilated pores
    • Blackheads
    • Blackheads
    • Acne scars
    • Bacterial inflammation
  • Active ingredients
    • Hyaluronic Acid
    • Royal Jelly extract
    • Nettle Protein
    • Aloe Vera
    • Burdock
    • Tripeptides
  • All the ingredients

    Aqua, Butylene Glycol, Peg-40 Hydrogenated Castor Oil, Sodium Hyaluronate, Niacinamide, Ethoxydi- glycol, Aloe Barbadensis Leaf Juice Powder, 10-Hydroxydecanoic Acid, Sebacic Acid, 1,10- Decanediol, Hydrolyzed Nettle Leaf Extract, Chlorhexidine Digluconate, Glycerin, Arctium Lappa Root Extract, Hyaluronic Acid, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Palmitoyl Tripeptide-8, Sodium Salicylate, Dextran, Imidazolidinyl Urea, Sorbic Acid, Citric Acid, Silanetriol, Potassium Sorbate.


EGF Rain

Marked skin and loss of firmness

Specially designed for sensitive and combination skin showing advanced signs of aging or blemishes. Each ingredient has been meticulously selected for its unique properties and its complementarity with the others. Enriched with hyaluronic acid, this serum offers an immediate plumping and smoothing effect. EGF/IGF stimulate cell repair and collagen production, visibly reducing wrinkles. Glucosamine improves epidermal firmness, while soybean oil extract selectively moisturizes, ensuring an even, radiant complexion.
  • Indication
    • Deep wrinkles
    • Sagging skin
    • Signs of aging
    • Scars
    • Stretch marks
  • Active ingredients
    • Hyaluronic Acid
    • Epidermal growth
    • (EGF + IGF)
    • Copper tripeptides
    • Polypeptides
    • Argireline
  • All the ingredients

    Aqua, Sodium Hyaluronate, Glycerin, Sac- charomyces Cerevisiae Extract, Saccharide Isomerate, Hyaluronic Acid, Hydroxypropyl Cyclodextrin, Ammonium Acryloyldimethyl- taurate/Vp Copolymer, Hydrogenated Lecithin, Sodium Oleate, Phenoxyethanol, Imidazolidinyl Urea, Butylene Glycol, Caprylyl Glycol, Glycine Soja Oil, Palmitoyl Tripeptide-38, Citric Acid, Silanetriol, Acetyl Tetrapeptide-40, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Copper Tripeptide-1, Sh-Oligopeptide- 2, Sh-Poly- peptide-3, Sodium Citrate, Sodium Benzoate, Sorbic Acid, 1,2-Hexanediol, Disodium Edta.

BTX Effect

Loose skin and loss of elasticity

To counter expression lines and loss of firmness, C-EM BTX effect is an effective, straightforward solution. Its rich hyaluronic acid content ensures an immediate smoothing effect on the skin. The inclusion of argireline and peptides specifically targets the density and depth of expression lines, offering a noticeable reduction. Used with microneedling, this serum is perfect for an express beauty makeover before a major event, promising immediate results that will strengthen over time.
  • Indication
    • Expression lines
    • Loss of elasticity
    • Loss of firmness
    • Immediate effect
  • Active ingredients
    • Hyaluronic Acid
    • DMAE
    • Glucosamine
    • BTX Peptides
  • All the ingredients

    Aqua, Glycerin, Sodium Hyaluronate, Dimethyl- aminoethanol Tartrate, Glucosamine Sulphate, Ammonium Acryloyldimethyltaurate/Vp Copo- lymer, Caprylyl Glycol, Hyaluronic Acid, Pheno- xyethanol, Dipeptide Diaminobutyroyl Benzyl- amide Diacetate, Palmitoyl Tripeptide-38, Acetyl Octapeptide-3, Pentapeptide-18, Acetyl Hexapeptide- 8, Silanetriol, Hydroxypropyl Cyclodextrin, Butylene Glycol, Citric Acid, Imidazolidinyl Urea, Sodium Benzoate, Sorbic Acid.

AOX Repair

Stressed skin and photoaging

Formulated to combat photoaging and everyday impacts on the skin, such as stress and pollution. Enriched with ingredients with powerful antioxidant properties such as vitamin C and niacinamides, this serum offers effective protection against external aggressors, while restoring skin hydration and promoting epidermal regeneration thanks to retinol, for revitalized, protected skin.
  • Indication
    • Dull complexion
    • Dryness
    • Photoaging
    • Various blemishes
    • Wrinkles caused by daily stress (stress, pollution, toxins, etc.)
  • Active ingredients
    • Hyaluronic Acid
    • Niacinamide (Vit.B3)
    • Vitamin C
    • Retinol (Vit.A)
    • Alpha-Lipoic Acid
    • Physalis extract
  • All the ingredients

    Aqua, Polysorbate 20, Niacinamide, Caprylic/ Capric Triglyceride, 3-O-Ethyl Ascorbic Acid, Sodium Hyaluronate, Physalis Angulata Extract, Retinol, Dimethyl Isosorbide, Thioctic Acid, Ferulic Acid, Hydroxymethoxyphenyl Deca- none, Hydroxypinacolone Retinoate, Pheno- xyethanol, Imida-zolidinyl Urea, Dimethyl- methoxy Chromanol, Ammonium Acryloyl- dimethyltaurate/Vp Copolymer, Melatonin, Cyanocobalamin, Hyaluronic Acid, Silanetriol, Citric Acid, Tocopherol, Lycopene, Sorbic Acid, Butylene Glycol, Bht, Disodium Edta.


Eye Perfect

Eye contour

A serum specially designed for the eye contour area, with a dual action on puffiness, dark circles and wrinkles. First, hyaluronic acid helps to smooth the eye contour and rehydrate the area. Peptides then stimulate collagen production to smooth wrinkles and restore skin elasticity. Finally, caffeine improves blood circulation to combat puffiness and puffiness.
  • Indication
    • Pockets
    • Dark circles
    • Crow's feet
    • Fine lines around the eyes
    • Slack eyelids
  • Active ingredients
    • Hyaluronic Acid
    • Vitamin C
    • Niacinamide (Vit.B3)
    • Peptides
    • Haloxyl
    • Glucosamine
  • All the ingredients

    Aqua, Sodium Hyaluronate, Ascorbyl Tetra- isopalmitate, Niacinamide, Glucosamine Sul- phate, Lecithin, Glycerin, Caffeine, Ruscus Acu- leatus Root Extract, Tea-Hydroiodide, Malus Domestica Fruit Cell Culture Extract, Acacia Senegal Gum, Carnitine, Helianthus Annuus Seed Oil, Hyaluronic Acid, Escin, Hedera Helix Leaf/Stem Extract, Phenoxyethanol, Butylene Glycol, Ammonium Acryloyldimethyltaurate/ Vp Copolymer, Imidazolidinyl Urea, Silane- triol, Steareth-20, Caprylyl Glycol, Malto- dextrin, Hydrated Silica, Citric Acid, N-Hydro- xysuccinimide, Chrysin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Tetrapeptide- 5, Carrageenan, Ascorbyl Palmitate, Tripep- tide-1, Menaquinone-7, Xanthan Gum, Potassium Sorbate, Sorbic Acid.

Hair Growth

Hair loss and density loss

This advanced formulation combines biomimetic growth factors and a vitamin complex to actively stimulate the proliferation of stem cells and their evolution into hair follicles. The beneficial effect is a significant slowdown in hair loss and an acceleration in hair growth, promoting denser, longer hair or beard.
  • Indication
    • Slow regrowth
    • Significant
    • significant
    • Loss of hair mass
    • Tired hair bulbs
  • Active ingredients
    • Hyaluronic Acid
    • Growth factors
    • (VEGF, EGF, KGF, IGF,
    • -FGF,
    • -FGF)
    • Copper tripeptides
    • Cyanocobalamin
  • All the ingredients

    Aqua, Sodium Hyaluronate, Ammonium Acryloyldimethyltaurate/vp Copolymer, Cyanocobalamin, Hydrogenated Lecithin, Sodium Oleate, Glycine- Soja Oil, Glycerin, Sh-Oligopeptide-2, Sh-polypeptide-1, Sh-polypeptide-11, Copper Tripeptide-1, Sh-Polypeptide-3, Sh-Polypeptide-9, Hyalu- ronic Acid, Butylene Glycol, Silanetriol, Phenoxyethanol, Imidazolidinyl Urea, CitricAcid, Sorbic Acid, Disodium Edta.

What our customers say

Hundreds of institutes place their trust in us.

A must-have for my salon

Ever since I introduced C-PEN with C-EM serums in my institute, my customers have been amazed by the results. Their skin is visibly smoother and firmer after each session. It's a worthwhile investment.

— Mei Ling
Oriental beauty

Visible, lasting results

My customers are always amazed to see results immediately after the treatment. And these results become more and more visible as the days go by, up to 6 weeks after the treatment. It's truly impressive.

— Ingrid S
Svensson Esthétique

Needle-free mesotherapy

These serums are perfectly suited to mesotherapy with or without needles, which is why I recommend them to all my customers.

— Lydia R

FAQ about C-EM sera

Your questions about celestetic professional microneedling serums.

Have unanswered questions?


Feel free to contact our advisors for any inquiries! They are ready to listen and guide you towards the best solutions for your needs.

No miracle, just science.

Celestetic is the leading Belgian medical aesthetics laboratory. Our mission is to blend technological innovations with scientific advancements to bring truly effective professional skincare products and solutions to the market. No false promises, no storytelling. With transparency and honesty.

Product Quality

Ingredients whose efficacy has been scientifically proven

Professional Training

For perfect mastery of techniques

Compliance with European Standards

Devices and products designed in compliance with European laws and standards

Solid and Quality Support

We accompany you in the long term and remain attentive to your needs

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